Autistic Disorder
Autistic disorder is a developmental disorder that affects a person's ability to communicate, form
relationships with others, and respond appropriately to the environment. Some people with autistic
disorder are high functioning, with speech and intelligence intact. Others may be nonverbal and/or
mentally retarded.
Asperger Disorder
Asperger disorder, sometimes referred to as Asperger syndrome, is a neurobiological disorder.
In contrast to autistic disorder, individuals with Asperger disorder do not have a delay in
spoken language development. However, they can have serious deficits in social and communication
skills. They often have obsessive, repetitive routines and preoccupations with a particular subject
matter.
Pervasive Developmental Disorder Not Otherwise Specified (PDD/NOS)
PDD/NOS is a diagnosis often considered for children who show some signs of autistic disorder, but
who do not meet the specific diagnostic criteria for the other PDDs.
Rett Disorder
Rett disorder is a complex neurological disorder that affects mainly girls, but there are reports
of males who this disorder. Rett disorder is genetic in origin, and is among the most common genetic
cause of profound intellectual and physical disability in girls, occurring more commonly than 1 in
10,000 female births. Individuals with Rett disorder develop normally until 6 to 18 months of age
followed by a developmental regression. This regression is followed by a deceleration of head growth,
loss of purposeful hand movements and followed by the appearance of midline, stereotypic hand movements.
A gene for Rett disorder was identified in 1999.
Childhood Disintegrative Disorder
Children with childhood Disintegrative disorder develop normally for a relatively prolonged period
(usually 2 to 4 years) before developing a condition that resembles autistic disorder. Typically
language, interest in the social environment, and often toileting and self-care abilities are lost,
and there may be a general loss of interest in the environment.
Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, 1994, pg. 65-78.