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Genetics Overview
What is a Chromosome?
Just as genes come in pairs, chromosomes also come in pairs. Each cell in
our body has 23 pairs of chromosomes (for a total of 46); one member of each pair is inherited from the
mother and the other is inherited from the father. The first 22 pairs (numbered 1 through 22) are called
autosomes and they determine most of our features. The last pair is called the sex chromosomes and they
determine if we are male or female. Females have two X chromosomes and males have one X chromosome and
one Y chromosome.
It is possible to tell the chromosomes apart by their size and their "banding pattern." The banding
pattern is a result of a chemical staining process used in the laboratory to help researchers see the
chromosomes more easily. Each chromosome is divided into two sections or "arms." The short arm is called
the "p" arm and the long arm is called the "q" arm. The bands on each arm are numbered. When researchers
study the chromosomes (a process called chromosome analysis) they try to determine if there are any missing
or extra pieces of the chromosomes.
[back to main Genetics Overview page]
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WHAT IS A GENE?
Genes are very small structures inside almost every cell of
the body. They are the instructions, or blueprints, that tell
our body how to grow and develop, build necessary proteins,
and thus determine an individual's characteristics, such as
eye color and blood type. More ...
HOW GENES ARE NAMED
You may wonder how genes are named. As you may have guessed,
some names are abbreviations for the full gene names. Other
genes are named after similar genes in other organisms. More ...
HOW CHROMOSOME ABNORMALITIES HELP US FIND GENES
Genetic researchers use many different tools and strategies to
look at the genetic material (DNA) inside our cells to find the
exact gene(s) that cause a genetic disorder such as autism. More ...
HOW GENOME SCREENS HELP US FIND GENES
In order to determine the genes that may be involved, scientists
also perform what are referred to as "genome screens." To do this
they use maps of the chromosomes in order to look for genes. More ...
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